Polyionenes (PI) with stable positive charges and tunable hydrophobic spacers in the polymer backbone, are shown to be particularly efficient regarding antimicrobial properties. This effect can be modulated since it increases with the length of hydrophobic spacers, i.e., the number of methylene groups between quaternary ammoniums. Now, to further explore these properties and provide efficient antimicrobial surfaces, polyionenes should be grafted onto materials. Here a robust grafting strategy to covalently attach polyionenes is described. The method consisted in a sequential surface chemistry procedure combining polydopamine coating, diazonium‐induced polymerization, and polyaddition. To the best of knowledge, grafting of PI onto surfaces is not reported earlier. All chemical steps are characterized in detail via various surface analysis techniques (FTIR, X‐ray photoelectron spectroscopy, contact angle, and surface energy measurements). The antibacterial properties of polyionene‐grafted surfaces are then studied through bacterial adhesion experiments consisting in enumeration of adherent bacteria (total and viable cultivable cells). PI‐grafted surfaces are showed to display effective and versatile bacteriostatic/bactericidal properties associated with a proadhesive effect.

中文翻译：

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聚紫罗烯的稳健接枝：新型强效多功能抗菌表面。

在聚合物骨架中具有稳定正电荷和可调疏水间隔基的聚紫罗烯 (PI) 被证明在抗菌性能方面特别有效。这种效应可以调节，因为它随着疏水间隔基的长度，即季铵之间的亚甲基数量而增加。现在，为了进一步探索这些特性并提供有效的抗菌表面，应将聚紫罗烯接枝到材料上。这里描述了一种共价连接聚紫罗烯的强大接枝策略。该方法包括结合聚多巴胺涂层、重氮诱导聚合和加聚反应的连续表面化学程序。据了解，之前没有报道过将 PI 接枝到表面上。所有化学步骤都通过各种表面分析技术（FTIR、X 射线光电子能谱、接触角和表面能测量）进行详细表征。然后通过细菌粘附实验研究聚紫罗烯接枝表面的抗菌特性，包括粘附细菌（总和可培养的可培养细胞）的计数。PI 接枝的表面显示出有效且多功能的抑菌/杀菌特性，并具有促粘附作用。