This study investigated the effects of babassu and coconut oil supplementation in breast cancer patients. This randomized clinical trial included 60 patients divided into three groups: untreated control group (CG), babassu oil group (BG), and coconut oil group (COG). Fatigue, quality of life, depression, tumour necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and salivary IgA were analysed before and after 12 weeks of supplementation. Babassu supplementation decreased fatigue and improved quality of life but did not affect depression scores. Babassu also decreased TNF-α and IL-6 levels and increased IgA in saliva compared to the COG and CG. In conclusion, babassu oil supplementation reduced fatigue and improved the quality of life of breast cancer patients, and these outcomes are probably related to the immunomodulatory effects of babassu oil in reducing proinflammatory cytokines and increasing IgA antibody production. These findings indicate that babassu oil may be useful as a supplement to reduce cancer-related fatigue.

这项研究调查了补充巴巴苏和椰子油对乳腺癌患者的影响。这项随机临床试验包括60位患者，分为三组：未治疗的对照组（CG），巴巴苏油组（BG）和椰子油组（COG）。在补充12周之前和之后分析疲劳，生活质量，抑郁，肿瘤坏死因子-α（TNF-α），白细胞介素6（IL-6）和唾液IgA。Babassu补充剂减少了疲劳并改善了生活质量，但没有影响抑郁评分。与COG和CG相比，Babassu还降低了唾液中的TNF-α和IL-6水平，并增加了IgA。总之，巴巴苏油补充剂可减轻乳腺癌患者的疲劳并改善其生活质量，这些结果可能与巴巴苏油在减少促炎细胞因子和增加IgA抗体产生方面的免疫调节作用有关。这些发现表明，巴巴苏油可作为减少癌症相关疲劳的补充剂。