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Focal adenomyosis of the outer myometrium and deep infiltrating endometriosis severity
Fertility and Sterility ( IF 6.7 ) Pub Date : 2020-10-01 , DOI: 10.1016/j.fertnstert.2020.05.003
Louis Marcellin 1 , Pietro Santulli 1 , Mathilde Bourdon 2 , Chloe Maignien 2 , Laetitia Campin 3 , Marie-Christine Lafay-Pillet 3 , Anne-Elodie Millischer 4 , Corinne Bordonne 5 , Bruno Borghese 2 , Bertrand Dousset 6 , Charles Chapron 1
Affiliation  

OBJECTIVE To determine whether the presence of focal adenomyosis of the outer myometrium (FAOM) at preoperative magnetic resonance imaging is associated with the severity of deep infiltrating endometriosis. DESIGN Observational cross-sectional study involving 255 symptomatic deep infiltrating endometriosis patients. Comparisons were performed according to the presence of FAOM. SETTING University hospital. PATIENT(S) Women with a preoperative magnetic resonance imaging and complete surgical exeresis of endometriotic lesions with histologically documented deep infiltrating endometriosis. INTERVENTION(S) Surgical management for deep infiltrating endometriosis. MAIN OUTCOME MEASURE(S) The presence of multiple deep infiltrating endometriosis lesions, the mean number and location of deep infiltrating endometriosis lesions, and the mean total revised American Society for Reproductive Medicine scores. RESULT(S) The prevalence of FAOM at preoperative magnetic resonance imaging in the 255 patients with deep infiltrating endometriosis was 56.5%. The mean number of deep infiltrating endometriosis lesions was significantly higher in the FAOM(+) group than in the FAOM(-) group: 3.5 ± 2.1 vs. 2.2 ± 1.5. The mean total revised American Society for Reproductive Medicine score was higher in case of FOAM coexisting with deep infiltrating endometriosis. After adjusting for confounding factors, the presence of FAOM was significantly associated with multiple deep lesions. CONCLUSION(S) FAOM was significantly associated with greater deep infiltrating endometriosis severity. This needs to be integrated into the management strategy. Furthermore, a pathogenic link between deep infiltrating endometriosis and FAOM cannot be excluded.

中文翻译:

外肌层局灶性子宫内膜异位症和深部浸润性子宫内膜异位症的严重程度

目的 确定术前磁共振成像中外肌层(FAOM)局灶性子宫内膜异位症的存在是否与深部浸润性子宫内膜异位症的严重程度相关。设计 观察性横断面研究,涉及 255 名有症状的深部浸润性子宫内膜异位症患者。根据FAOM的存在进行比较。设置大学医院。PATIENT(S) 术前磁共振成像和子宫内膜异位病变的完整手术锻炼的女性,组织学记录为深浸润性子宫内膜异位症。干预(S) 深部浸润性子宫内膜异位症的手术治疗。主要观察指标 是否存在多个深部浸润性子宫内膜异位病灶,深部浸润性子宫内膜异位病灶的平均数量和位置,以及修订后的美国生殖医学学会评分的平均总分。结果 255 名深部浸润性子宫内膜异位症患者术前磁共振成像中FAOM 的患病率为56.5%。在FAOM(+) 组中,深层浸润性子宫内膜异位病变的平均数量显着高于FAOM(-) 组:3.5 ± 2.1 对2.2 ± 1.5。在 FOAM 与深部浸润性子宫内膜异位症共存的情况下,美国生殖医学会修订后的平均总分更高。在调整混杂因素后,FAOM 的存在与多个深部病变显着相关。结论(S)FAOM 与更深的浸润性子宫内膜异位症严重程度显着相关。这需要纳入管理战略。此外,
更新日期:2020-10-01
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