The purpose of this study was to evaluate the surface and in vitro cytotoxicity on human dysplastic oral keratinocytes (DOK) of four commercial resins-based dental composites commonly used in prosthodontics dental therapies: two indirect composites for crown and bridges—SR Adoro (IvoclarVivadent GmbH) and Solidex (Shofu Dental GmbH); and two dual-curing luting resin cements—RelyxUnicem (3M ESPE Dental Products) and Variolink Esthetic DC (IvoclarVivadentGmbH). A complex assessment of surface characteristics of the four materials was conducted before and after the exposure to artificial saliva through various analyses, such as Scanning Electron Microscopy, Atomic Force Microscopy and Cross Polarized Light Microscopy (PLM). The results showed that DOK viability was not severely affected by exposure to any of these materials; however, Variolink expressed higher values but still above the toxicity level of the rest of the composites. The analysis of the surface structure between initial and artificial saliva exposed specimens returned a compact aspect in both categories and although Variolink and Relyx were subjected to increased roughness after saliva exposure, no damage of the internal compactness was recorded, demonstrating a fair behavior of the luting cements in contact with the saliva.

中文翻译：

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牙科复合材料的表面特性和细胞毒性评价

这项研究的目的是评估通常用于修复牙齿治疗的四种市售树脂基牙科复合材料对人发育异常的口腔角质形成细胞（DOK）的表面和体外细胞毒性：两种用于冠和桥的间接复合材料-SR Adoro（IvoclarVivadent GmbH ）和Solidex（Shofu Dental GmbH）；以及两种双固化胶粘树脂胶粘剂-RelyxUnicem（3M ESPE牙科产品）和Variolink Esthetic DC（IvoclarVivadentGmbH）。通过各种分析，例如扫描电子显微镜，原子力显微镜和交叉偏振光显微镜（PLM），在暴露于人造唾液之前和之后对这四种材料的表面特性进行了综合评估。结果表明，暴露于这些物质中的任何一个，DOK的生存能力均未受到严重影响。然而，Variolink表示较高的值，但仍高于其余复合材料的毒性水平。初始和人工唾液暴露标本之间的表面结构分析在这两个类别中都返回了一个紧凑的方面，尽管Variolink和Relyx在唾液暴露后经受了增加的粗糙度，但未记录到内部致密性的损坏，表明了诱饵的合理行为与唾液接触的水泥。