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The Short Overview on the Relevance of Fatty Acids for Human Cardiovascular Disorders.
Biomolecules ( IF 5.5 ) Pub Date : 2020-07-30 , DOI: 10.3390/biom10081127
Viktoriya S Shramko 1 , Yana V Polonskaya 1 , Elena V Kashtanova 1 , Ekaterina M Stakhneva 1 , Yuliya I Ragino 1
Affiliation  

This review presents existing evidence of the influence of saturated and unsaturated fatty acids on cardiovascular diseases (CVD). Data are discussed regarding the roles of the most relevant fatty acids, such as myristic (C14:0), palmitic (C16:0), stearic (C18:0), palmitoleic (C16:1), oleic (C18:1), linoleic (C18:2), α-linolenic (C18:3, ω-3), γ-linolenic (C18:3, ω-6), arachidonic (C20:4), eicosapentaenoic (C20:5), docosahexaenoic (C22:6), and docosapentaenoic (C22:5) acid. The accumulated knowledge has expanded the understanding of the involvement of fatty acids in metabolic processes, thereby enabling the transition from basic exploratory studies to practical issues of application of these biomolecules to CVD treatment. In the future, these findings are expected to facilitate the interpretation and prognosis of changes in metabolic lipid aberrations in CVD.

中文翻译:

脂肪酸与人类心血管疾病相关性的简短概述。

这篇综述提供了饱和和不饱和脂肪酸对心血管疾病(CVD)影响的现有证据。讨论了有关最相关脂肪酸的作用的数据,例如肉豆蔻酸(C14:0),棕榈酸(C16:0),硬脂酸(C18:0),棕榈油酸(C16:1),油酸(C18:1),亚油酸(C18:2),α-亚麻酸(C18:3,ω- 3 ),γ-亚麻酸(C18:3,ω-6),花生四烯酸(C20:4),二十碳五烯酸(C20:5),二十二碳六烯酸(C22:6)和十二碳五烯酸(C22:5)酸。积累的知识扩大了对脂肪酸参与代谢过程的了解,从而使人们能够从基本的探索性研究过渡到将这些生物分子应用于CVD治疗的实际问题。将来,这些发现有望促进CVD中代谢脂质异常变化的解释和预后。
更新日期:2020-07-30
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