All living entities are cognitive and dependent on ambiguous information. Any assessment of that imprecision is necessarily a measuring function. Individual cells measure information to sustain self-referential homeostatic equipoise (self-identity) in juxtaposition to the external environment. The validity of that information is improved by its collective assessment. The reception of cellular information obliges thermodynamic reactions that initiate a self-reinforcing work channel. This expresses as natural cellular engineering and niche constructions which become the complex interrelated tissue ecologies of holobionts. Multicellularity is collaborative cellular information management directed towards the optimization of information quality through its collective measured assessment. Biology and its evolution can now be re-framed as the continuous process of self-referential cellular measurement in the perpetual defense of individual cellular self-identities through the collective form.

所有生物都是认知性的，并且依赖于不明确的信息。对这种不精确性的任何评估都必须是一种测量功能。各个单元测量信息以维持与外部环境并列的自我指称稳态平衡（自我身份）。通过集体评估，该信息的有效性得以提高。细胞信息的接收迫使热力学反应启动了自我增强的工作通道。这表现为天然细胞工程和生态位构造，它们变成了整体生物的复杂的相互关联的组织生态。多细胞性是协作性蜂窝信息管理，旨在通过其集体测量评估来优化信息质量。