Industrialization and advancements in agriculture are increasingly the cause of environmental concerns and need to be addressed. This study was carried out at four sampling sites, viz. Manimuthar (site 1), Tirunelveli (site 2), Srivaikuntam (site 3), and Authoor (site 4), along the Thamirabarani river. The heavy metal concentration in fish and sediments were ranged from 0.001 to 9.505 mg kg⁻¹ and 0.294 to 106.25 mg kg⁻¹. The lifetime cancer risk (LCR) values for children and adults were found to be above the acceptable threshold value (ATV) and children were found to be more susceptible to health risks. For all sites except site 4, the LCR of toxic metals except Cd were within the ATV (10⁻⁶–10⁻⁴); the value of Cd was above the ATV, and poses a high cancer risk to the downstream inhabitants. This study advises routine heavy metal monitoring on aquatic organisms along these sites to implement regulatory standards.

农业的工业化和进步日益引起环境问题，需要加以解决。这项研究是在四个采样点进行的。沿着Thamirabarani河的Manimuthar（站点1），Tirunelveli（站点2），Srivaikuntam（站点3）和Authoor（站点4）。鱼和沉积物中的重金属浓度范围为0.001至9.505 mg kg ^-1和0.294至106.25 mg kg ^-1。发现儿童和成人的终生癌症风险（LCR）值高于可接受的阈值（ATV），并且发现儿童更容易受到健康风险的影响。对于除场地4以外的所有场地，除Cd之外的有毒金属的LCR均在ATV范围内（10 ^-6 –10 ^-4）; 镉的价值高于全地形车，对下游居民构成高癌症风险。这项研究建议对沿这些地点的水生生物进行常规重金属监测，以实施监管标准。