The current pandemic of COVID-19 and the identification of accessible biomarkers of disease progression is of clinical importance in the management of this novel and serious disease. This study was completed to provide information regarding 1 possible uniquely upregulated marker in this illness, eosinophil-derived neurotoxin (EDN-1). A literature search was undertaken to provide medical data regarding EDN-1 as a biomarker in the clinical setting. The literature identified was further analyzed to identify its use in the clinical setting of viral disease and asthma.

中文翻译：

---

嗜酸性粒细胞衍生的神经毒素和呼吸道感染和炎症：对COVID-19管理的意义。

当前COVID-19的大流行以及疾病进展的可利用生物标记物的鉴定在这种新型严重疾病的治疗中具有重要的临床意义。这项研究的完成是为了提供有关这种疾病中可能存在的一种唯一上调的标志物-嗜酸性粒细胞衍生的神经毒素（EDN-1）的信息。进行了文献检索，以提供有关EDN-1在临床环境中作为生物标志物的医学数据。对所鉴定的文献进行进一步分析，以确定其在病毒性疾病和哮喘的临床环境中的用途。