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Medicinal Properties of Lilium candidum L. and Its Phytochemicals.
Plants ( IF 4.658 ) Pub Date : 2020-07-29 , DOI: 10.3390/plants9080959
Michele Zaccai 1 , Ludmila Yarmolinsky 2 , Boris Khalfin 2, 3 , Arie Budovsky 4 , Jonathan Gorelick 2 , Arik Dahan 3 , Shimon Ben-Shabat 3
Affiliation  

Lilium candidum L., known as Madonna, meadow, or white lily, is a bulbous plant from the Liliaceae family, originating in the Middle East. L. candidum has been abundantly used in folk medicine since ancient times to relieve a variety of ailments, including age-related diseases, burns, ulcers, and coughs. The aim of this article is to investigate the anti-inflammatory and anti-diabetic activities of L. candidum extracts and its active phytochemicals. Some active volatile phytochemicals were identified using gas chromatography–mass spectrometry (GC-MS) analysis. Significant (p < 0.001) anti-diabetic properties of the extracts kaempferol, linalool, citronellal, and humulene were demonstrated by an elevation in glucose uptake by adipocytes. The significant (p < 0.01) effect of the plant extracts kaempferol, citronellal, and humulene on the secretion of pro-inflammatory cytokines interleukin 6 (IL-6) and interleukin 8 (IL-8) was demonstrated using enzyme-linked immunosorbent assay. Altogether, L. candidum and its rich collection of phytochemicals hold promising medicinal potential, and further investigations of its therapeutic prospects are encouraged.

中文翻译:

白花百合的药用特性及其植物化学成分。

假丝酵母百合,被称为麦当娜,草甸或白百合,是百合科的鳞茎植物,起源于中东。自古以来,念珠菌已被广泛用于民间医学,以减轻各种疾病,包括与年龄有关的疾病,烧伤,溃疡和咳嗽。本文的目的是研究念珠菌提取物及其活性植物化学物质的抗炎和抗糖尿病活性。使用气相色谱-质谱(GC-MS)分析鉴定了一些活性挥发性植物化学物质。显著(p<0.001)提取物山奈酚,芳樟醇,香茅醛和草烯的抗糖尿病特性通过脂肪细胞对葡萄糖的摄取增加来证明。使用酶联免疫吸附试验证明了植物提取物山emp酚,香茅醛和腐殖质对促炎细胞因子白介素6(IL-6)和白介素8(IL-8)分泌的显着(p <0.01)作用。总之,L.石斛及其丰富的植物化学物质的集合持有看好医药潜力,并鼓励其治疗前景的进一步调查。
更新日期:2020-07-29
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