Study Objective

Endometriosis is a recognized cause of pelvic pain in adolescents with menstrual symptoms that significantly affect education, activity, and social interactions. We aim to provide an updated systematic review of the prevalence of endometriosis in adolescents with pelvic pain presenting for gynecological investigation.

Data Sources

We searched Medline, Embase, and Cinahl from 2011 to July 2019.

Methods of Study Selection

We included cohort studies of adolescents with pelvic pain undergoing gynecological investigation. Two authors independently selected studies and extracted study characteristics and prevalence data. Methodological quality was assessed using the Critical Appraisal Skills Program for cohort studies.

Results

This updated systematic review evaluated a total of 19 studies including 1243 symptomatic adolescents. In all, 648 of 1011 (64%) adolescents undergoing laparoscopy were found to have endometriosis. The prevalence ranged from 25% to 100%, with a mean prevalence of 64%. Thirteen studies including 381 participants categorized disease severity using the revised American Society of Reproductive Medicine classification. Among these, 53% of participants (201/381) had stage I, 28% (105/381) had stage II, 20% (76/381) had stage III, and 13% (49/381) had stage IV disease.

Conclusions

The prevalence of endometriosis among adolescents with pelvic pain symptoms is high. Endometriosis is treatable, and prompt recognition will help to ensure that adolescents are signposted earlier to appropriate specialists. The management of adolescents with suspected endometriosis should be consistent with best practice guidance. Despite recommendations to increase the awareness and knowledge of endometriosis in adolescence, minimal research has followed.

中文翻译：

---

骨盆痛青少年子宫内膜异位症的患病率：系统评价。

研究目的

子宫内膜异位症是公认的青少年盆腔痛的病因，月经症状严重影响教育，活动和社交活动。我们旨在为妇科研究的盆腔痛青少年提供子宫内膜异位症患病率的最新系统评价。

数据源

从2011年到2019年7月，我们搜索了Medline，Embase和Cinahl。

方法

研究选择：我们纳入了接受妇科研究的骨盆疼痛青少年的队列研究。两位作者独立选择研究，提取研究特征和患病率数据。方法学质量使用关键评估技能计划进行队列研究。

结果

这项更新的系统评价评估了总共19项研究，包括1243例有症状的青少年。1011名接受腹腔镜检查的青少年中，共有648名（64％）患有子宫内膜异位症。患病率从25％到100％不等，平均患病率为64％。13项研究（381名参与者）使用修订后的美国生殖医学学会分类法对疾病严重程度进行了分类。其中，I期为53％（201/381），II期为28％（105/381），III期为20％（76/381），IV期为13％（49/381）。

结论

在骨盆疼痛症状的青少年中，子宫内膜异位症的患病率很高。子宫内膜异位症是可以治疗的，并且迅速得到认可，可以确保将青少年提前签到合适的专家处。怀疑有子宫内膜异位的青少年的治疗应符合最佳实践指导。尽管建议增加青春期子宫内膜异位症的认识和知识，但很少进行研究。