The giant panda (Ailuropoda melanoleuca) is a rare species with a small global population size, and lives in the wild in only a few fragmented mountain ranges of Southwest China. Parasitic infections are among the important causes of death of giant pandas that hamper their group development. We reviewed the parasitic infections prevailing in giant pandas, and the parasitic diversity, diseases and their impact on conservation of this animal. A total of 35 parasitic species were documented in giant pandas, belonging to nematode (n = 6), trematode (n = 1), cestode (n = 2), protozoa (n = 9), and ectozoa (n = 17 (tick = 13, mite = 2, and flea = 2)). Among them, Baylisascaris schroederi had the highest prevalence and was the leading cause of death for giant pandas. Some parasites caused asymptomatic infections in giant pandas, and their health implications for the pandas remain unknown. As a whole, parasites are reported to be an important threat to the conservation of the giant pandas. Regular deworming and environmental disinfection appear to be effective ways to prevent captive giant pandas from parasitoses. In wild panda populations, parasitic control measures are suggested to include detailed examination of the ecology of the host-parasite assembly, with particular attention to density-dependent transmission. The parasitic pathogenesis and detection methods together with their biology, epidemiology, treatment, prevention and control need to be further studied for better protection of giant pandas from parasitoses.