A novel and green synthesis of 1-phenyl isoquinoline derivatives has been developed by using Ru(II)/PEG-400 as homogeneous recyclable catalyst via C-H/N-N bond activation via C-H/N-N functionalization of 1-(diphenylmethylene) hydrazine and aryl substituted acetylenes. In order to realize the proposed protocol, Cu(OAc)₂ and AgSbF₆ are used as oxidant and additive respectively in PEG-400 biodegradable solvent. This protocol has a simple extraction procedure, uses biodegradable solvent, affords high atom economy, employs a reusable catalytic system, provides wide substrate scope with high yield of product, for the synthesis of isoquinoline derivatives.

中文翻译：

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使用Ru（II）/ PEG-400作为CH / NN键活化的均相可循环催化剂，绿色合成异喹啉

通过使用Ru（II）/ PEG-400作为均相可循环利用的催化剂，通过CH / NN键活化，通过1-（二苯基亚甲基）肼和芳基取代的乙炔的CH / NN官能化，开发了一种新颖的绿色的1-苯基异喹啉衍生物。。为了实现所提出的方案，在PEG-400生物可降解溶剂中分别使用Cu（OAc）₂和AgSbF ₆作为氧化剂和添加剂。该方案具有简单的提取程序，使用可生物降解的溶剂，提供了高原子经济性，采用了可重复使用的催化体系，提供了广泛的底物范围和高产率的产物，用于合成异喹啉衍生物。