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Synthesis and antibacterial studies on some new thiazole moiety based quinolone derivatives
Indian Journal of Chemistry, Section B ( IF 0.456 ) Pub Date : 2019-12-16
Nivedita Srivastava, Anil Kumar, Arti Mehrotra

Thiazole moiety at C-3 position based quinolone derivatives have been synthesized from the starting material aniline and its derivatives. All synthesized compounds in this series have been tested for in vitro antibacterial activity against E. coli (ETEC), S. typhi, P. aeruginosa and S. aureus. All synthesized compound have been tested with reference drugs viz., norfloxacin and ciprofloxacin.

中文翻译:

一些新的基于噻唑基的喹诺酮衍生物的合成和抗菌研究

由起始物质苯胺及其衍生物合成了基于C-3位的噻唑部分的喹诺酮衍生物。已测试该系列中所有合成的化合物对大肠杆菌(ETEC),鼠伤寒沙门氏菌铜绿假单胞菌金黄色葡萄球菌的体外抗菌活性。所有合成的化合物均已用参比药物,诺氟沙星和环丙沙星进行了测试。
更新日期:2019-12-16
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