Plant mediated synthesis of nanoparticles is a better substitute for chemically synthesized nanoparticles. These nanoparticles facilitate more advantages in cancer treatment. In this study, biosynthesis of gold nanoparticles has been carried out using aqueous extract of Eichhornia crassipes (Mart.) Solms by the hot air-oven method. The effect of variation of plant extract concentration was carried out to optimize the formation of gold nanoparticles by this method. Reduced graphene oxide was prepared by treating graphene oxide with aqueous extract of E. crassipes as a capping agent. Nano composite was prepared using an equal ratio of reduced graphene oxide and nanogold by sonication method. Prepared metal and non-metallic nanoparticles were characterized by analytical spectroscopic tools viz. UV-Visible spectrometer, FTIR spectrophotometer, and Field Emission Scanning Electron Microscope. Cell viability of aforesaid nanoparticles was examined by MTT assay against MCF-7 cell lines. Among all the nanoparticles, reduced graphene oxide exhibited 23% cell viability at 250 μg /mL and IC50 at 140 μg /mL against MCF-cell lines. Doxorubicin was used as a standard. The result of this study reveals the cytotoxicity of the prepared nanoparticles and nanocomposite against MCF-cell lines.

中文翻译：

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金纳米粒子还原氧化石墨烯复合材料在MCF-7细胞系上的细胞生存能力评估

植物介导的纳米粒子的合成是化学合成纳米粒子的更好的替代品。这些纳米颗粒促进了癌症治疗的更多优势。在该研究中，已经通过热风烤箱方法使用凤眼莲（Sichms）的水提取物进行了金纳米颗粒的生物合成。通过这种方法进行了植物提取物浓度变化的影响，以优化金纳米颗粒的形成。还原的氧化石墨烯是通过用景天链球菌的水提取物作为封闭剂处理氧化石墨烯来制备的。通过超声法，使用等比例的还原氧化石墨烯和纳米金制备纳米复合材料。制备的金属和非金属纳米颗粒通过分析光谱工具表征。紫外可见分光光度计FTIR分光光度计 和场发射扫描电子显微镜。通过MTT测定针对MCF-7细胞系检查了上述纳米颗粒的细胞生存力。在所有纳米颗粒中，还原的氧化石墨烯在250μg/ mL的条件下对MCF细胞系表现出23％的细胞活力，在140μg/ mL的条件下显示出IC50。以阿霉素为标准。这项研究的结果揭示了制备的纳米颗粒和纳米复合材料对MCF细胞系的细胞毒性。