The partitioning of cells into groups or ‘compartments’ separated by straight and sharp boundaries is important for tissue formation in animal development. Cells from neighboring compartments are characterized by distinct fates and functions and their continuous separation at compartment boundaries maintains proper tissue organization. Signaling across compartment boundaries can induce the local expression of morphogens that in turn direct growth and patterning of the surrounding cells. Compartment boundaries play therefore an important role in tissue development. Compartment boundaries were first identified in the early 1970s in the Drosophila wing. Here, we review the role of compartment boundaries in growth and patterning of the developing wing and then discuss the genetic and physical mechanisms underlying cell separation at compartment boundaries in this tissue.

将细胞分成由直线和尖锐边界分隔的组或“隔室”对于动物发育中的组织形成很重要。来自相邻隔室的细胞具有不同的命运和功能，它们在隔室边界处的连续分离保持了适当的组织组织。跨越隔室边界的信号传导可以诱导形态发生素的局部表达，进而指导周围细胞的生长和模式化。因此，隔室边界在组织发育中起着重要作用。1970 年代初在果蝇中首次确定了隔室边界翅膀。在这里，我们回顾了隔室边界在发育中的翅膀的生长和图案形成中的作用，然后讨论了在该组织的隔室边界处细胞分离的遗传和物理机制。