We report two cases of interventional radiologists who had been exposed to radiation while performing fluoroscopically-guided interventional procedures (FGIPs), mainly transcatheter arterial chemoembolization, percutaneous catheter drainage, and percutaneous transhepatic biliary drainage procedures, for over 10 years. They had a unique multi-aberrant cell type with not only high numbers of dicentrics and/or centric rings but also excess acentric double minutes, similar to a rogue cell. As revealed in a self-administered questionnaire, they wore personal dosimeters and protective equipment at all times and used shielding devices during interventional fluoroscopy procedures. However, the exposed dose levels derived from cytogenetic dosimetry were much higher than the doses recorded on their personal dosimeters. A large number of unstable and stable chromosomal aberrations that were found in the peripheral blood lymphocytes of these interventional radiologists might be due to repeated and long-term exposure to ionizing radiation while performing FGIPs. Further investigations of chromosomal aberrations in interventional radiologists may improve the understanding of the long-term effects of radiation exposure on medical personnel.

我们报告了 2 例介入放射科医师在进行透视引导介入手术 (FGIP) 时暴露于辐射的病例，这些手术主要是经导管动脉化疗栓塞、经皮导管引流和经皮经肝胆道引流术，超过 10 年。它们具有独特的多异常细胞类型，不仅具有大量双着丝粒和/或中心环，而且还有过多的无着丝粒双分钟，类似于流氓细胞。正如一份自我管理的问卷所揭示的那样，他们始终佩戴个人剂量计和防护设备，并在介入透视程序期间使用屏蔽装置。然而，从细胞遗传学剂量学得出的暴露剂量水平远高于他们个人剂量计上记录的剂量。在这些介入放射科医生的外周血淋巴细胞中发现的大量不稳定和稳定的染色体畸变可能是由于在执行 FGIP 时反复和长期暴露于电离辐射。介入放射科医生对染色体畸变的进一步研究可能会增进对辐射暴露对医务人员的长期影响的理解。