An 8-y-old Labrador Retriever was presented to a small animal practice in northern Virginia with a history of recent lethargy. Physical examination findings were unremarkable. Ultrasound revealed several large hepatic masses and multiple smaller masses involving the pancreas. Cytologic findings on fine-needle aspirates of the hepatic masses included inflammation and necrosis with eosinophilic, membranous oval structures consistent with cestode infection. Histopathologic findings for biopsies of these masses included extensive necrosis, inflammation, and PAS-positive hyaline-like membranous material interpreted as metacestode cyst wall. A PCR product was generated from aspirate material using primers specific for Echinococcus multilocularis. Subsequent sequence data were 100% homologous to E. multilocularis NADH dehydrogenase subunit I gene sequences. The dog received daily oral albendazole (10 mg/kg) treatment, but its condition deteriorated, and the dog was euthanized. The dog, born in Mississippi, was brought as a puppy to Virginia with no other travel history. To our knowledge, alveolar echinococcosis has not been reported previously in a dog in the United States; E. multilocularis infection was apparently acquired in the mid-Atlantic region of the United States.

一个八岁的拉布拉多猎犬被送往弗吉尼亚北部的一家小动物饲养场，该病有近期嗜睡的历史。体检发现无异常。超声检查发现有几个大的肝脏肿块和多个较小的肿块累及胰腺。肝肿块细针抽吸物的细胞学发现包括炎症和坏死，嗜酸性，膜性椭圆形结构与c虫感染一致。对这些肿块进行活组织检查的组织病理学发现包括广泛的坏死，炎症和PAS阳性的透明样膜状物质，被认为是前囊肿囊壁。从抽出物产生的PCR产物使用特异棘球E虫引物。后续序列数据与100％同源E. multilocularis NADH脱氢酶亚基I基因序列。这只狗每天接受口服阿苯达唑（10 mg / kg）治疗，但病情恶化，对它实施安乐死。这只狗在密西西比州出生，是一只小狗带到弗吉尼亚，没有其他旅行史。据我们所知，在美国，以前没有在狗中报告过肺泡棘球co病。在美国中大西洋地区显然获得了多眼大肠杆菌的感染。