当前位置: X-MOL 学术Cartilage › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Autologous Minced Cartilage Implantation for Treatment of Chondral and Osteochondral Lesions in the Knee Joint: An Overview.
CARTILAGE ( IF 2.8 ) Pub Date : 2020-07-25 , DOI: 10.1177/1947603520942952
Gian M Salzmann 1, 2 , Robert Ossendorff 3 , Ron Gilat 4 , Brian J Cole 4
Affiliation  

Cartilage defects in the knee are being diagnosed with increased frequency and are treated with a variety of techniques. The aim of any cartilage repair procedure is to generate the highest tissue quality, which might correlate with improved clinical outcomes, return-to-sport, and long-term durability. Minced cartilage implantation (MCI) is a relatively simple and cost-effective technique to transplant autologous cartilage fragments in a single-step procedure. Minced cartilage has a strong biologic potential since autologous, activated non-dedifferentiated chondrocytes are utilized. It can be used both for small and large cartilage lesions, as well as for osteochondral lesions. As it is purely an autologous and homologous approach, it lacks a significant regulatory oversight process and can be clinically adopted without such limitations. The aim of this narrative review is to provide an overview of the current evidence supporting autologous minced cartilage implantation.



中文翻译:

自体碎软骨植入治疗膝关节软骨和骨软骨损伤:概述。

膝关节软骨缺损的诊断频率越来越高,并采用多种技术进行治疗。任何软骨修复程序的目的都是产生最高的组织质量,这可能与改善临床结果、恢复运动和长期耐用性有关。碎软骨植入 (MCI) 是一种相对简单且具有成本效益的技术,可通过单步程序移植自体软骨碎片。由于使用了自体、活化的非去分化软骨细胞,因此碎软骨具有很强的生物学潜力。它既可用于小型和大型软骨病变,也可用于骨软骨病变。由于它纯粹是一种自体和同源的方法,因此缺乏重要的监管过程,并且可以在没有这些限制的情况下在临床上采用。

更新日期:2020-07-25
down
wechat
bug