Development of a biocatalytic cascade for synthesis of 2-oxo-4-(hydroxymethylphosphinyl) butyric acid in one pot,Biocatalysis and Biotransformation

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Development of a biocatalytic cascade for synthesis of 2-oxo-4-(hydroxymethylphosphinyl) butyric acid in one pot
Biocatalysis and Biotransformation ( IF 1.8 ) Pub Date : 2020-07-25 , DOI: 10.1080/10242422.2020.1797697
Jianmiao Xu _{1,

2} , Kai Zhang _{1,

2} , Huiting Cao _{1,

2} , Heng Li _{1,

2} , Feng Cheng _{1,

2} , Chenghao Cao _{1,

2} , Ya-Ping Xue _{1,

2} , Yu-Guo Zheng _{1,

2}

Affiliation

2-Oxo-4-(hydroxymethylphosphinyl) butyric acid (PPO) is an important precursor compound for the broad-spectrum herbicide l-glufosinate (L-PPT). In this study, the gene of d-amino acid oxidase (DAAO...

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