Techno-economic analysis is an important part of evaluating potential chemical manufacturing ventures. A proposed conceptual process design gives the design engineer most of the information required to conduct these analyses. However, developing conceptual designs can be time consuming and expensive, especially given that most conceptual designs never see commercialization. In this work, we present a rapid screening methodology to generate screening-level economic metrics (NPV and NPV_%) without dedicating significant time or resources to conventional chemical process design. This methodology uses ultimate bounds on reaction selectivity combined with the minimum work of separations to bypass the design procedure altogether. The methodology presented here provides a means to rapidly screen chemistries for their economic merit, compare a proposed process design to the best-case economic scenario, and compare potential projects competing for the same funding sources. In this article, we present the necessary theory and demonstrate the methodology.

技术经济分析是评估潜在化工生产企业的重要组成部分。提出的概念性过程设计为设计工程师提供了进行这些分析所需的大多数信息。但是，开发概念设计可能既耗时又昂贵，特别是考虑到大多数概念设计从未实现商业化。在这项工作中，我们提出了一种快速筛查方法来生成筛查级经济指标（NPV和NPV _％），而无需花费大量时间或资源进行常规化学工艺设计。这种方法结合了反应选择性的最终界限和最小的分离工作，从而完全绕开了设计程序。此处介绍的方法提供了一种方法，可以快速筛选化学品的经济价值，将拟议的工艺设计与最佳情况的经济方案进行比较，并比较竞争相同资金来源的潜在项目。在本文中，我们介绍了必要的理论并论证了方法论。