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A New Austalide from Penicillium sp. SO01
Chemistry of Natural Compounds ( IF 0.8 ) Pub Date : 2020-07-01 , DOI: 10.1007/s10600-020-03117-9
Jia Wang , Yining Sang , Siqi Tang , Peng Zhang

Five austalide meroterpenoids, including a new one named 13-deoxyaustalide Q acid methyl ester, were isolated from the ethyl acetate extract of the fungus Penicillium sp. SO01. The structure of the new compound was determined on the basis of IR, UV, HR-ESI-MS NMR spectra and CD data. The cytotoxicities of compound 1 against three human tumor cell lines were also tested, with IC50 values of 27.66 μM (SW-1990 cell line), 28.77 μM (Hep3B cell line), and 39.93 μM (HepG2 cell line).

中文翻译:

来自青霉菌属的新 Austalide。SO01

从真菌 Penicillium sp. 的乙酸乙酯提取物中分离出五种 austalide meterpenoids,包括一种名为 13-deoxyaustalide Q 酸甲酯的新化合物。SO01。新化合物的结构是根据 IR、UV、HR-ESI-MS NMR 光谱和 CD 数据确定的。还测试了化合物 1 对三种人类肿瘤细胞系的细胞毒性,IC50 值为 27.66 μM(SW-1990 细胞系)、28.77 μM(Hep3B 细胞系)和 39.93 μM(HepG2 细胞系)。
更新日期:2020-07-01
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