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Regiodivergent Ring Opening Reactions of 2-Arylated 3-Nitrocyclopropane-1,1-Dicarboxylates Leading to Polyfunctionalized Dipoles
Heterocycles ( IF 0.6 ) Pub Date : 2020-07-09 , DOI: 10.3987/com-20-s(k)21
Haruyasu Asahara, Rikiya Kamidate, and Nagatoshi Nishiwaki

Two kinds of Lewis acid induced ring-opening reactions of 2-aryl-3-nitrocyclopropane-1,1-dicarboxylates proceeded to afford 5-aryl-2-isoxazolines and γ-keto acid derivatives, respectively. Different ring-opening modes could be controlled by choosing the ligand or solvent.

中文翻译:

2-芳基化的3-硝基环丙烷-1,1-二羧酸酯的区域发散性开环反应导致多官能化偶极子

两种路易斯酸引起的2-芳基-3-硝基环丙烷-1,1-二羧酸酯的开环反应分别得到5-芳基-2-异恶唑啉和γ-酮酸衍生物。可以通过选择配体或溶剂来控制不同的开环模式
更新日期:2020-08-15
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