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The Role of Gastric Mucosal Immunity in Gastric Diseases.
Journal of Immunology Research ( IF 4.1 ) Pub Date : 2020-07-24 , DOI: 10.1155/2020/7927054
Siru Nie 1, 2, 3 , Yuan Yuan 1, 2, 3
Affiliation  

Gastric mucosa plays its immune function through innate and adaptive immunity by recruiting immune cells and releasing corresponding cytokines, which have an inseparable relationship with gastric diseases. Whether infective gastric diseases caused by Helicobacter pylori, Epstein-Barr virus or other microbe, noninfective gastric diseases, or gastric cancer, gastric mucosal immunity plays an important role in the occurrence and development of the disease. Understanding the unique immune-related tissue structure of the gastric mucosa and its role in immune responses can help prevent gastric diseases or treat them through immunotherapy. In this review, we summarize the basic feature of gastric mucosal immunity and its relationship with gastric diseases to track the latest progress of gastric mucosal immunity, update relevant knowledge and provide theoretical reference for the prevention and treatment of gastric diseases based on the gastric mucosal immunity.

中文翻译:

胃粘膜免疫在胃病中的作用。

胃粘膜通过募集免疫细胞并释放相应的细胞因子,通过先天性和适应性免疫发挥其免疫功能,这与胃疾病有着不可分割的关系。无论是由幽门螺杆菌,爱泼斯坦-巴尔病毒或其他微生物引起的感染性胃病,非感染性胃病还是胃癌,胃粘膜免疫在该病的发生和发展中都起着重要作用。了解胃黏膜独特的免疫相关组织结构及其在免疫反应中的作用可以帮助预防胃病或通过免疫疗法治疗胃病。在这篇综述中,我们总结了胃粘膜免疫的基本特征及其与胃病的关系,以追踪胃粘膜免疫的最新进展,
更新日期:2020-07-24
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