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Nontoxic pH-sensitive silver nanocomposite hydrogels for potential wound healing applications
Polymer-Plastics Technology and Materials ( IF 2.7 ) Pub Date : 2020-07-11 , DOI: 10.1080/25740881.2020.1786584
S. Sudarsan 1 , M. S. Selvi 2 , G. Chitra 3 , M. Sakthivel 2 , D. S. Franklin 2 , S. Guhanathan 2
Affiliation  

Silver nanocomposite (SNC) containing pH sensitivity with fascinating attention may be recommended for extensive utilization in eco-friendly nanomaterial applications. In the present investigation, a strategy to fabricate new biodegradable and biocompatible hydrogels based on sodium alginate/ethylene glycol/acrylic acid functionalized with silver nanocomposites, which were synthesized by a facile greener method. The swelling profile is enhanced the stimuli responsive behavior of nanocomposite hydrogels. The synthesized nanocomposite hydrogels has showed a significant pH-sensitive behavior which induced the degradation profile, cell viability, and antimicrobial activity. Hence, this kind of biomaterials has been utilized for nontoxic, degradable wound healing dressing.



中文翻译:

无毒的pH敏感型银纳米复合水凝胶可用于潜在的伤口愈合应用

推荐将pH敏感的银纳米复合材料(SNC)吸引人,以在生态友好的纳米材料应用中广泛使用。在本研究中,一种基于藻酸钠/乙二醇/丙烯酸被银纳米复合材料官能化的新型可生物降解和生物相容性水凝胶的制备策略,是通过一种简便的绿色方法合成的。溶胀曲线增强了纳米复合水凝胶的刺激响应行为。合成的纳米复合水凝胶显示出显着的pH敏感行为,可诱导降解曲线,细胞活力和抗菌活性。因此,这种生物材料已被用于无毒,可降解的伤口愈合敷料。

更新日期:2020-07-24
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