Abstract

Alternaria alternata JS-1623 is an endophytic fungus isolated from a stem tissue of Korean fir, Abies koreana. Ethyl acetate extracts of culture filtrates exhibited anti-inflammatory activity in LPS induced microglia BV-2 cell without cytotoxicity. Here we report a 33.67 Mb sized genome assembly of JS-1623 comprised of 13 scaffolds with N50 of 4.96 Mb, and 92.41% of BUSCO completeness. GC contents were 50.97%. Of the 11,197 genes annotated, gene families related to the biosynthesis of secondary metabolites or transcription factors were identified.

中文翻译：

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朝鲜冷杉内生真菌 Alternaria alternata JS-1623 的基因组序列草案

摘要

Alternaria alternata JS-1623 是从红杉 ( Abies koreana)的茎组织中分离出来的内生真菌。培养滤液的乙酸乙酯提取物在 LPS 诱导的小胶质细胞 BV-2 细胞中表现出抗炎活性，且无细胞毒性。在这里，我们报告了 33.67 Mb 大小的 JS-1623 基因组组装，由 13 个支架组成，N50 为 4.96 Mb，BUSCO 完整性为 92.41%。GC含量为50.97%。在注释的 11,197 个基因中，鉴定了与次级代谢物或转录因子的生物合成相关的基因家族。