Lupus nephritis (LN) is a common complication of systemic lupus erythematosus (SLE), which is a chronic autoimmune disease. However, the detailed mechanisms underlying this disorder have remained unclear. Alpha2‐antiplasmin (α2AP) is known to perform various functions, such as plasmin inhibition and cytokine production, and to be associated with immune and inflammatory responses.

中文翻译：

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α2AP 通过调节纤溶酶抑制和炎症反应与狼疮性肾炎的发展有关。

狼疮性肾炎（LN）是系统性红斑狼疮（SLE）的常见并发症，系统性红斑狼疮是一种慢性自身免疫性疾病。然而，这种疾病背后的详细机制仍不清楚。已知 α2-抗纤溶酶 (α2AP) 具有多种功能，如纤溶酶抑制和细胞因子产生，并与免疫和炎症反应有关。