Active (thio)esters and amides were prepared from carboxylic acids and several reagents containing 2‐pyridyl or pyrimidyl moiety. Active (thio)carbonates, thionocarbonate, and thiourea were prepared from (thio)phosgene and 2‐hydroxypyridine or 2‐mercaptopyridine. The acylation of active (thio)esters and amides containing 2‐pyridyl or pyrimidyl groups with various organometallics afforded ketones, aldehydes, esters, amides, and β‐keto esters. The alkoxycarbonylation of active (thio)carbonates with Grignard reagents and amines afforded esters and carbamates, respectively. Active di(thiono)carbonates and thiourea containing the 2‐pyridyl or pyrimidyl moiety have been used in the dehydration of carboxylic acids/alcohols or aldoximes, dehydrosulfurization of thioureas, and (thio)carbonyl transfer of diols or amines to produce esters or nitriles, carbodiimides, cyclic carbonates or isothiocyanates, respectively.

中文翻译：

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2-吡啶基和嘧啶相关试剂的合成和多功能利用

活性（硫代）酯和酰胺是由羧酸和几种含有2-吡啶基或嘧啶基的试剂制备的。活性（硫代）碳酸酯，硫代碳酸根和硫脲是由（硫代）光气和2-羟基吡啶或2-巯基吡啶制备的。含有2-吡啶基或嘧啶基的活性（硫代）酯和酰胺与各种有机金属的酰化作用可得到酮，醛，酯，酰胺和β-酮酯。用格氏试剂和胺对活性（硫代）碳酸酯进行烷氧基羰基化反应，分别得到酯和氨基甲酸酯。含有2-吡啶基或嘧啶基的活性碳酸二（硫代）碳酸酯和硫脲已用于羧酸/醇或醛肟的脱水，硫脲的脱硫以及二醇或胺的（硫）羰基转移以生成酯或腈，