A micro-invasive technique is presented that enables pigment sampling from individual layers of a painting cross-section by obtaining a furrow 10–50 μm wide of chosen length. Combined with increased sensitivity of lead (Pb) isotope analysis using multicollector inductively coupled plasma mass spectrometry (MC-ICPMS) equipped with a 1013 Ω resistor or a Pb double-spike technique, the amount of Pb needed for isotopic analysis is drastically reduced, while maintaining a relative 2 SD precision for 206Pb/204Pb of < 0.02%. The methodology proved able to characterize Pb isotope differences within paint layers.

中文翻译：

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一种研究绘画中铅同位素的微创方法

提出了一种微创技术，通过获得 10-50 微米宽的选定长度的沟，可以从绘画横截面的各个层进行颜料采样。结合使用配备 1013 Ω 电阻器或 Pb 双尖峰技术的多接收器电感耦合等离子体质谱仪 (MC-ICPMS) 提高铅 (Pb) 同位素分析的灵敏度，同位素分析所需的 Pb 量显着减少，同时保持 206Pb/204Pb 的相对 2 SD 精度 < 0.02%。该方法证明能够表征涂料层内的 Pb 同位素差异。