High-intensity focused ultrasound (HIFU) is a minimally invasive technique of regional treatment in which ultrasound waves are focused on targeted tissue. Nevertheless, the precise localization of the target area of HIFU ablation remains challenging. This study investigated acoustic pressure, fluid flow, and heat transfer in porous tissue during exposure to HIFU. The effects of the heat transfer model, tissue permeability, and exposure time on fluid flow and temperature distribution in the tissue were numerically investigated. Additionally, the heating-region shape and heating position were studied. The acoustic pressure, fluid flow, and temperature distributions in the porous tissue during exposure to HIFU were calculated using the numerical simulation of acoustic wave propagation and heat transfer models. The heat transfer models used were formulated based on the conventional bioheat model and porous media theory. With the porous media model, the temperature distributions were observed to be different from those of the conventional bioheat model; this was caused by the acoustic streaming effect. Permeability affected the flow pattern and temperature distribution in the tissue. In particular, tissue permeability also has a significant effect on the position of the target area and lesion shape within the tissue.

高强度聚焦超声（HIFU）是一种将区域聚焦于目标组织的超声波的微创技术。然而，HIFU切除目标区域的精确定位仍然具有挑战性。这项研究调查了HIFU暴露期间多孔组织中的声压，流体流动和传热。数值研究了传热模型，组织渗透性和暴露时间对组织中流体流动和温度分布的影响。另外，研究了加热区域的形状和加热位置。使用声波传播和传热模型的数值模拟，计算了HIFU暴露期间多孔组织中的声压，流体流量和温度分布。使用的传热模型是基于常规生物热模型和多孔介质理论制定的。在多孔介质模型中，观察到的温度分布与传统的生物热模型不同。这是由声流效应引起的。渗透性影响组织中的流动模式和温度分布。特别地，组织渗透性也对组织内目标区域的位置和病变形状具有显着影响。