当前位置: X-MOL 学术J. King Saud Univ. Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Effects of pomegranate juice on the sexual behavior, fertility and protective activity against aluminum exposure in male mice
Journal of King Saud University-Science ( IF 3.8 ) Pub Date : 2020-06-18 , DOI: 10.1016/j.jksus.2020.06.002
Mohsen Ghaleb Al-Mutary , Gasem Mohammad Abu-Taweel

This experiment aimed to determine how pomegranate juice (PJ) responds to oxidative stress induced by aluminum in male mice. A total of thirty-six male mice were separated into six groups. The first group (control group) received tap water. Groups two and three were given 20% and 40% PJ, respectively. Group four received 400 mg Al/kg, while groups five and six were given Al + 20% PJ and Al + 40% PJ, respectively. After the oral administration period, the sexual behavior of the mice was recorded. Blood was collected from the heart to measure testosterone concentration. After the animals were sacrificed, the reproductive organs were weighed, and the epididymis and testis were used for further evaluations. Our findings showed that Al decreased the body and organs weights, sexual behavior, sperm count, normal sperm, total and progressive sperm motility, testosterone level, and epithelial diameters of the seminiferous tubes. In addition, the PJ reduced these effects and minimized the aluminum toxicity in male mice. In conclusion, PJ protects against aluminum exposure in male mice by ameliorating sexual behavior and fertility.



中文翻译:

石榴汁对雄性小鼠性行为,生育力和铝暴露保护作用的影响

该实验旨在确定石榴汁(PJ)对铝引起的雄性小鼠氧化应激反应的方式。将总共​​三十六只雄性小鼠分成六组。第一组(对照组)接受自来水。第二和第三组分别给予20%和40%的PJ。第四组接受400 mg Al / kg,而第五和第六组分别接受Al + 20%PJ和Al + 40%PJ。口服给药后,记录小鼠的性行为。从心脏收集血液以测量睾丸激素浓度。处死动物后,称重生殖器官,并将附睾和睾丸用于进一步评估。我们的研究结果表明,铝降低了人体和器官的重量,性行为,精子数量,正常精子,精液总的和进行的精子运动,睾丸激素水平和上皮直径。此外,PJ降低了这些作用,并使铝对雄性小鼠的毒性最小化。总之,PJ可通过改善性行为和生育能力来防止雄性小鼠接触铝。

更新日期:2020-06-18
down
wechat
bug