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Acupuncture in the treatment of stable chronic obstructive pulmonary disease: A systematic review of randomised controlled trials
Journal of King Saud University-Science ( IF 3.8 ) Pub Date : 2020-04-09 , DOI: 10.1016/j.jksus.2020.04.001
Xiong Xiao , Shu Li , Zhi Cao , Yan Wang

Objective

To systematically evaluate the clinical efficacy and safety of acupuncture in the treatment of chronic obstructive pulmonary disease (COPD).

Methods

Randomised controlled trials (RCTs) of acupuncture and/or transcutaneous electrical nerve stimulation over acupoints (acu-TENS) in the treatment of the stable COPD were searched in PubMed, Embase, The Cochrane Library, WanFang Data, VIP, CNKI and CBM databases from the respective inception to January 2019. Literature screening and data extraction were independently performed by two researchers and methodological quality was assessed using the Cochrane Collaboration Risk of Bias Tool. Outcome measures included treatment efficiency, quality of life, lung function, activity tolerance and adverse events were evaluated.

Results

Eleven RCTs involving 709 patients were included. The results showed that the treatments of COPD, acupuncture and/or acu-TENS could improve the treatment efficiency compared with the control group [RR = 1.11, 95%CI (1.02 to 1.21), P = 0.02], improve the quality of life [MD = −3.66, 95%CI (−5.56 to −1.76), P = 0.0002], increased percentage of forced expiratory volume in 1 s (FEV1%) [MD = 8.75, 95%CI (0.98 to 16.51), P = 0.03], increased predicted forced vital capacity (FVC%) value [MD = 7.93, 95%CI (1.83 to 14.03), P = 0.01], increased FVC(L) [MD = 0.16, 95%CI (0.01 to 0.30), P = 0.04] and decreased Borg score [MD = -3.00, 95%CI (-3.99 to −2.01), P = 0.00001]. Only 3 cases reported mild contusion and pain.

Conclusions

Our systematic review shows that the combination of acupuncture with medications and/or rehabilitation exercise may increase efficacy in stable COPD treatment by alleviating the clinical symptoms and improving the quality of life.



中文翻译:

针灸治疗稳定的慢性阻塞性肺疾病:随机对照试验的系统评价

目的

目的系统评价针灸治疗慢性阻塞性肺疾病(COPD)的临床疗效和安全性。

方法

在PubMed,Embase,Cochrane图书馆,WanFang数据,VIP,CNKI和CBM数据库中检索了针灸和/或经穴位经皮电神经刺激(acu-TENS)治疗稳定型COPD的随机对照试验(RCT)。分别于2019年1月开始。两名研究人员独立进行文献筛选和数据提取,并使用Cochrane协作偏倚风险工具评估了方法学质量。结果指标包括治疗效率,生活质量,肺功能,活动耐受性和不良事件。

结果

纳入了涉及709名患者的11项RCT。结果表明,与对照组相比,COPD,针刺和/或acu-TENS的治疗可提高治疗效率[RR = 1.11,95%CI(1.02至1.21),P  = 0.02],可改善生活质量[MD = -3.66,95%CI(-5.56至-1.76),P  = 0.0002],在1 s内增加的呼气量百分比(FEV1%)[MD = 8.75,95%CI(0.98至16.51),P  = 0.03],增加的预计强制肺活量(FVC%)值[MD = 7.93、95%CI(1.83至14.03),P  = 0.01],增加的FVC(L)[MD = 0.16、95%CI(0.01至0.30) ),P  = 0.04]和Borg分数降低[MD = -3.00,95%CI(-3.99至-2.01),P = 0.00001]。仅3例报告轻度挫伤和疼痛。

结论

我们的系统评价显示,针灸与药物和/或康复锻炼的结合可以通过缓解临床症状和改善生活质量来提高稳定型COPD治疗的疗效。

更新日期:2020-04-09
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