After months of restrictive containment efforts to fight the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) epidemic, European countries are planning to reopen. To support the process, we conducted a cross-sectional survey among the Hungarian population to estimate the prevalence of infectious cases and prior SARS-CoV-2 exposure. A representative sample (n = 17,787) for the Hungarian population of 14 years or older living in private households (n = 8,283,810) was selected. The study was performed within 16 days after 50 days of restrictions, when the number of confirmed cases was stable low. Naso- and oropharyngeal smears and blood samples were collected for PCR and antibody testing. The testing was accompanied by a questionnaire about symptoms, comorbidities, and contacts. Design-based prevalence estimates were calculated. In total, 10,474 individuals (67.7% taken into account a sample frame error of 2315) of the selected sample participated in the survey. Of the tested individuals, 3 had positive PCR and 69 had positive serological test. Population estimate of the number of SARS-CoV-2 infection and seropositivity were 2421 and 56,439, respectively, thus active infection rate (2.9/10,000) and the prevalence of prior SARS-CoV-2 exposure (68/10,000) was low. Self-reported loss of smell or taste and body aches were significantly more frequent among those with SARS-CoV-2. In this representative, cross-sectional survey of the Hungarian population with a high participation rate, the overall active infection rate was low in sync with the prevalence of prior SARS-CoV-2 exposure. We demonstrated a potential success of containment efforts, supporting an exit strategy. NCT04370067, 30.04.2020.

中文翻译：

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匈牙利人群中新型冠状病毒的流行，这是一项横断面的全国性调查，旨在支持匈牙利的出口政策。

经过数月的限制性遏制努力，以抗击严重的急性呼吸系统综合症冠状病毒2（SARS-CoV-2）流行，欧洲国家计划重新开放。为了支持这一过程，我们在匈牙利人群中进行了横断面调查，以估计传染病的患病率和先前的SARS-CoV-2暴露。 居住在私人家庭中的14岁以上匈牙利人口的代表性样本（n = 17,787）（n = 8,283,810）。该研究在禁忌症50天后的16天内进行，当时确诊病例数稳定在低水平。收集鼻和口咽涂片和血样用于PCR和抗体测试。测试伴随有关于症状，合并症和接触的问卷。计算了基于设计的患病率估计。总共10,474个人（67.7％，考虑到2315的样本框架误差）来自所选样本。在测试的个体中，3例PCR阳性，69例血清学检测阳性。人群估计的SARS-CoV-2感染数量和血清反应阳性分别为2421和56,439，因此活动感染率（2.9 / 10,000）和以前的SARS-CoV-2感染率（68 / 10,000）低。自我报告的嗅觉或味觉丧失以及身体疼痛在SARS-CoV-2患者中明显更为频繁。在该代表性的横断面调查中，参与率较高的匈牙利人口中，总体活跃感染率较低，与先前的SARS-CoV-2暴露患病率同步。我们展示了遏制努力的潜在成功，并支持退出策略。NCT04370067，2020年4月30日。