Objectives. This study investigated the relationship between quality of life (QOL) and several factors, including pain assessments, in patients with rheumatoid arthritis (RA). Methods. This cross-sectional, single-center study enrolled 85 patients with RA. The variables investigated included demographic characteristics, the 28-joint disease activity score with C-reactive protein (DAS28-CRP), painDETECT questionnaire (PDQ), pain self-efficacy questionnaire (PSEQ), and pain catastrophizing scale (PCS). QOL was measured using the Japanese validated version of the European Quality of Life questionnaire with five dimensions and five levels (EQ-5D-5L). Results. The use of oral steroids and oral analgesics was significantly associated with low EQ-5D-5L scores (). EQ-5D-5L score had a significant positive association with PSEQ (r = 0.414) and significant negative association with age, disease duration, DAS28-CRP, PDQ, and PCS (r = −0.217, −0.343, −0.217, −0.277, and −0.384, respectively). Multiple regression analysis showed that the use of oral analgesics and PSEQ were independent predictors of EQ-5D-5L score (β = -0.248, and β = 0.233, ). Conclusions. The use of oral analgesics by RA patients may influence their QOL, which, in turn, may affect their feelings of self-efficacy. Various pain management strategies, including surgical treatment, may be explored for the treatment of RA. Furthermore, the PSEQ may be a prominent part of the patient’s overall assessment.

中文翻译：

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口服镇痛药的使用和疼痛的自我效能感是类风湿关节炎患者生活质量的独立预测指标。

目标。这项研究调查了类风湿关节炎（RA）患者的生活质量（QOL）与几个因素之间的关系，包括疼痛评估。方法。这项横断面，单中心研究招募了85名RA患者。调查的变量包括人口统计学特征，具有C反应蛋白的28关节疾病活动评分（DAS28-CRP），painDETECT问卷（PDQ），疼痛自我效能感问卷（PSEQ）和疼痛灾难性量表（PCS）。使用日本验证版的《欧洲生活质量问卷》对生活质量进行测量，该问卷具有五个维度和五个级别（EQ-5D-5L）。结果。口服类固醇和口服镇痛药的使用与EQ-5D-5L分数低显着相关（）。EQ-5D-5L得分与PSEQ呈显着正相关（ r  = 0.414），而与年龄，疾病持续时间，DAS28-CRP，PDQ和PCS呈显着负相关（ r  = -0.217，-0.343，-0.217，-0.277 ，和-0.384）。多元回归分析表明，口服镇痛药和PSEQ是EQ-5D-5L得分的独立预测因子（ β  = -0.248，和β  = 0.233，）。 结论。RA患者使用口服镇痛药可能会影响他们的QOL，进而影响他们的自我效能感。可以探索各种疼痛治疗策略，包括外科治疗，以治疗RA。此外，PSEQ可能是患者总体评估的重要部分。