Lung injury with COVID-19 may be due to a complex underlying pathophysiology. Cytokine release syndrome appears to be a catalyst of different inflammatory pathways promoting lung parenchymal injury and thromboembolic phenomena (“dual hit” injury). Recently, severe neurological manifestations such as acute disseminated encephalomyelitis, which may be not linked to lung pathology, have been identified in COVID-19, contributing thus further to the versatility of its clinical features.

中文翻译：

---

COVID-19 中的肺损伤——一个新的假设。

COVID-19 引起的肺损伤可能是由复杂的潜在病理生理学造成的。细胞因子释放综合征似乎是不同炎症途径的催化剂，促进肺实质损伤和血栓栓塞现象（“双重打击”损伤）。最近，在 COVID-19 中发现了严重的神经系统表现，例如急性播散性脑脊髓炎，可能与肺部病理无关，这进一步促进了其临床特征的多功能性。