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Comparative larvicidal effect of Pterodon spp. extracts obtained by different extraction methods
The Journal of Supercritical Fluids ( IF 3.9 ) Pub Date : 2020-07-24 , DOI: 10.1016/j.supflu.2020.104993
Felipe Zaniol , Jean F.F. Calisto , Gilberto Cozzer , Diego M. Ferro , Jônatas L. Dias , Luiz G.G. Rodrigues , Simone Mazzutti , Renan S. Rezende , Daniel A. Simões , Sandra R.S. Ferreira , Jacir Dal Magro , J. Vladimir Oliveira

Pterodon spp. is a native Brazilian tree species of Fabaceae family, popularly known as sucupira. In the present study, the extraction methods of Soxhlet, supercritical fluid extraction (SFE) and ultrasound assisted extraction (UAE) were conducted at different conditions to recover compounds from “sucupira” with larvicidal activity against Aedes aegypti larvae. The influence of temperature and pressure on SFE with CO2 was compared to Soxhlet and UAE techniques, performed with hexane and ethanol as solvents. The use of ethanol as solvent provided better yields, but lower larvicidal activity. The extraction yields obtained with CO2 and hexane as solvents (non-polar) were similar, regardless the extraction method. Non-polar solvents showed better larvicidal activity with chances of having practical applications in fighting disease vectors. The chemical composition of these extracts presented as major components, trans-geranylgeraniol, germacrene-D-ol and caryophyllene, which showed to be responsible for the activity.



中文翻译:

翼龙属的比较杀幼虫作用。通过不同提取方法获得的提取物

翼龙属 是Fabaceae家族的巴西原生树种,俗称sucupira。在本研究中,索氏提取法,超临界流体提取法(SFE)和超声辅助提取法(UAE)在不同条件下进行,以从“ sucupira”中回收对埃及伊蚊幼虫具有杀幼虫活性的化合物。将温度和压力对采用CO 2的SFE的影响与以己烷和乙醇为溶剂的Soxhlet和UAE技术进行了比较。使用乙醇作为溶剂可提供更高的收率,但杀幼虫活性较低。用CO 2获得的提取产率不论萃取方法如何,其与己烷作为溶剂(非极性)均相似。非极性溶剂显示出更好的杀幼虫活性,并有可能在抗击病媒中得到实际应用。这些提取物的化学成分为主要成分,即反式香叶基香叶醇,胚芽戊二烯-D-ol和石竹烯,它们是造成这种活性的原因。

更新日期:2020-07-24
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