Bioorthogonal nanofactories have emerged in the last decade to provide xenobiotic pathways that generate nonbiological substances in living environments. In this issue of Chem, Qu and co-workers incorporate asymmetric catalytic properties and chemotactic capabilities into novel nanodevices to achieve the stereo- and site-selective synthesis of the active enantiomer of ibuprofen at inflammation sites.

中文翻译：

---

生物正交催化手性

在过去的十年中，已经出现了生物正交的纳米工厂，以提供在生活环境中产生非生物物质的异生物途径。在本期《化学》杂志中，Qu及其同事将不对称的催化特性和趋化能力纳入了新型纳米器件中，以实现布洛芬活性对映异构体在炎症部位的立体和位点选择性合成。