Opportunistic fungal pathogens have increased in frequency with the growing immunosuppressed population. New and emerging pathogens, including the rare yeasts, continue to cause significant morbidity and mortality and frequently develop despite prophylaxis with antifungal agents. We report a previously unreported manifestation of disseminated trichosporonosis. Our patient with underlying acute myeloid leukemia presented with as an exophytic toe lesion found secondary to Trichosporon asahii. We highlight the need for a high index of suspicion to diagnose breakthrough infections and the need for aggressive treatment.

中文翻译：

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毛孢子菌病表现为外生性皮肤肿块。

随着免疫抑制人群的增加，机会性真菌病原体的频率增加。新出现的病原体，包括稀有酵母菌，继续导致显着的发病率和死亡率，尽管使用抗真菌剂进行了预防，但仍经常发生。我们报告了以前未报告的播散性毛孢子菌病的表现。我们的急性髓细胞白血病患者基本呈现作为外生性脚趾病变发现继发于丝孢asahii。我们强调需要高度怀疑来诊断突破性感染和积极治疗的需要。