Secondary compounds from plants are often insecticidal. Rutin, a plant bioflavonoid, has demonstrated insect control activity. We studied the survival, growth, and detoxifying enzyme activities of grasshopper Oedaleus asiaticus Bey-Bienko (Orthoptera: Acrididae) exposed to rutin using an artificial indoor feeding trial and field cage study for three years. O. asiaticus had reduced growth rate and decreased survival when exposed to rutin. The 7-day LC50 was 763.7 mg/L. Rutin induced an elevated level of reactive oxygen species (ROS) representing oxygen damage. Activities of antioxidant enzymes, superoxide dismutase (SOD), catalase (CAT), and peroxidase (POD); and the detoxifying enzymes, cytochrome P450s (CYP450s), UDP-glucuronosyltransferase (UGTs), carboxylesterase (CarEs), and glutathione-S-transferase (GSTs) were all significantly increased when Oedaleus asiaticus exposed to rutin. Rutin was toxic to O. asiaticus and suppressed grasshopper growth. The detrimental effects of rutin to O. asiaticus offer a new option for the development of biological pesticides and potential application to grasshopper biological control.

中文翻译：

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蚱蜢Oedaleus asiaticus (Orthoptera: Acrididae) 暴露于有毒芦丁后的存活、生长和解毒酶活性

来自植物的次生化合物通常具有杀虫作用。芦丁是一种植物生物类黄酮，已证明具有昆虫控制活性。我们使用人工室内饲养试验和田间笼子研究三年来研究了暴露于芦丁的蚱蜢 Oedaleus asiaticus Bey-Bienko（直翅目：蝗科）的存活、生长和解毒酶活性。O. asiaticus 在暴露于芦丁时生长速度降低，存活率降低。7 天 LC50 为 763.7 mg/L。芦丁诱导代表氧损伤的活性氧 (ROS) 水平升高。抗氧化酶、超氧化物歧化酶 (SOD)、过氧化氢酶 (CAT) 和过氧化物酶 (POD) 的活性；和解毒酶、细胞色素 P450s (CYP450s)、UDP-葡萄糖醛酸转移酶 (UGTs)、羧酸酯酶 (CarEs)、当 Oedaleus asiaticus 暴露于芦丁时，谷胱甘肽-S-转移酶（GST）均显着增加。芦丁对 O. asiaticus 有毒并抑制蚱蜢生长。芦丁对 O. asiaticus 的不利影响为生物农药的开发和蝗虫生物防治的潜在应用提供了新的选择。