Emotion regulation plays a central role in empathy. Only by successfully regulating our own emotions can we reliably use them in order to interpret the content and valence of others’ emotions correctly. In an functional magnetic resonance imaging (fMRI)-based experiment, we show that regulating one’s emotion via reappraisal modulated biased emotional intensity ratings following an empathy for pain manipulation. Task-based analysis revealed increased activity in the right inferior frontal gyrus (IFG) when painful emotions were regulated using reappraisal, whereas empathic feelings that were not regulated resulted in increased activity bilaterally in the precuneus, supramarginal gyrus and middle frontal gyrus (MFG), as well as the right parahippocampal gyrus. Functional connectivity analysis indicated that the right IFG plays a role in the regulation of empathy for pain, through its connections with regions in the empathy for pain network. Furthermore, these connections were further modulated as a function of the type of regulation used: in sum, our results suggest that accurate empathic judgment (i.e. empathy that is unbiased) relies on a complex interaction between neural regions involved in emotion regulation and regions associated with empathy for pain. Thus, demonstrating the importance of emotion regulation in the formulation of complex social systems and sheds light on the intricate network implicated in this complex process.

中文翻译：

---

重新评估疼痛的潜在神经网络。

情绪调节在移情中起核心作用。只有成功地调节自己的情绪，我们才能可靠地使用它们，以便正确地解释他人情绪的内容和效价。在基于功能磁共振成像（fMRI）的实验中，我们显示了通过对疼痛操作给予同情后，通过重新评估调制的偏向情绪强度等级来调节人的情绪。基于任务的分析显示，通过重新评估来调节疼痛情绪后，右下额叶回（IFG）的活动增加，而未受到调节的共情感觉则导致前额神经，上臀回和中额额回（MFG）的双边活动增加，以及右海马旁回。功能连接性分析表明，正确的IFG通过与疼痛共情网络中的区域连接，在疼痛共情调节中发挥作用。此外，根据所使用的调节类型进一步调节了这些联系：总而言之，我们的结果表明，准确的共情判断（即无偏见的共情）依赖于情绪调节所涉及的神经区域和与之相关的区域之间的复杂相互作用。同情痛苦。因此，证明了情绪调节在复杂社会系统的表述中的重要性，并阐明了在这个复杂过程中牵涉的复杂网络。这些联系被进一步根据所使用的调节类型进行调节：总而言之，我们的结果表明，准确的共情判断（即无偏见的共情）依赖于情绪调节所涉及的神经区域与与共情相关的区域之间的复杂相互作用。疼痛。因此，证明了情绪调节在复杂社会系统的表述中的重要性，并阐明了在这个复杂过程中牵涉的复杂网络。这些联系被进一步根据所使用的调节类型进行调节：总的来说，我们的结果表明，准确的共情判断（即无偏见的共情）依赖于情绪调节所涉及的神经区域与与共情相关的区域之间的复杂相互作用。疼痛。因此，证明了情绪调节在复杂社会系统的表述中的重要性，并阐明了在这个复杂过程中牵涉的复杂网络。