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Clinical and Morphological Spectrum of Histoplasmosis on Cytology Along with the Review of Literature.
Acta Cytologica ( IF 1.8 ) Pub Date : 2020-07-23 , DOI: 10.1159/000509151
Gargi Kapatia 1 , Ashmita Saha 1 , Manish Rohilla 1 , Parikshaa Gupta 1 , Nalini Gupta 1 , Radhika Srinivasan 1 , Arvind Rajwanshi 1 , Pranab Dey 2
Affiliation  

Objective: The aim of the study was to study the clinical and morphological spectrum of histoplasmosis diagnosed by fine needle aspiration cytology (FNAC). Study Design: A total of 17 patients diagnosed with histoplasmosis on FNAC were studied over a period of 5 years. The cytology smears were studied and analysed for the cytomorphological spectrum of histoplasmosis. Results: Among the 17 patients studied, the mean age was 51.3 years (range 6–84 years). Male-to-female ratio was 3.25:1 with 4 females and 13 males. The frequent sites of involvement were the lung (5), lymph node (4), adrenal gland (4), and skin (4). The most common cytological patterns were histiocytic collection, followed by granulomas and multinucleated giant cells. Necrosis was noted in only 4 cases. Conclusion: Fine needle aspiration is a highly accurate, rapid, and cheap technique for the diagnosis of histoplasmosis due to its distinct morphological features.
Acta Cytologica


中文翻译:

组织胞浆菌病的细胞形态学和形态学研究以及文献综述。

目的:研究目的是研究细针穿刺细胞学(FNAC)诊断出的组织胞浆菌病的临床和形态学谱。研究设计:在为期5年的研究中,总共对17名经FNAC诊断为组织胞浆菌病的患者进行了研究。对细胞学涂片进行了研究并分析了组织胞浆菌病的细胞形态谱。结果:在研究的17例患者中,平均年龄为51.3岁(6-84岁)。男女比例为3.25:1,其中4位女性和13位男性。累及的部位是肺(5),淋巴结(4),肾上腺(4)和皮肤(4)。最常见的细胞学模式是组织细胞收集,其次是肉芽肿和多核巨细胞。仅4例发现坏死。结论:细针抽吸由于其独特的形态学特征,是诊断组织胞浆菌病的一种高精度,快速且廉价的技术。
细胞学学报
更新日期:2020-07-23
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