People living with HIV (PLWH) and substance use disorder (SUD) are particularly vulnerable to harmful health consequences of the global COVID-19 pandemic. The health and social consequences of the pandemic may exacerbate substance misuse and poor management of HIV among this population. This study compares substance use and HIV care before and during the pandemic using data collected weekly through an opioid relapse prevention and HIV management mobile-health intervention. We found that during the pandemic, PLWH and SUD have increased illicit substance use and contact with other substance-using individuals and decreased their confidence to stay sober and attend recovery meetings. The proportion of people missing their HIV medications also increased, and confidence to attend HIV follow-up appointments decreased. Optimal support for PLWH and SUD is critical during pandemics like COVID-19, as drug-related and HIV antiretroviral therapy (ART) non-adherence risks such as overdose, unsafe sexual behaviors, and transmission of infectious diseases may unfold.

艾滋病毒感染者 (PLWH) 和物质使用障碍 (SUD) 患者特别容易受到全球 COVID-19 大流行带来的有害健康后果的影响。大流行的健康和社会后果可能会加剧该人群的药物滥用和艾滋病毒管理不善。这项研究使用通过阿片类药物复发预防和 HIV 管理移动健康干预每周收集的数据，比较了大流行之前和期间的物质使用和 HIV 护理。我们发现，在大流行期间，PLWH 和 SUD 增加了非法物质的使用和与其他物质使用者的接触，并降低了他们保持清醒和参加康复会议的信心。错过艾滋病毒药物治疗的人的比例也增加了，参加艾滋病毒随访预约的信心下降。