Myocardial perfusion imaging is a commonly performed SPECT protocol and hence it would be beneficial if its scan duration could be shortened. For traditional gamma cameras, two developments have separately shown to allow for a shortened scan duration: (i) reconstructing with Monte Carlo-based scatter correction instead of dual-energy window scatter correction and (ii) acquiring projections with the SMARTZOOM collimator instead of a parallel-hole collimator. This study investigates which reduction in scan duration can be achieved when both methods are combined in a single system. The SMARTZOOM collimator was implemented in a Monte Carlo-based reconstruction package and the implementation was validated through image quality phantom experiments. The potential for scan duration reduction was evaluated with a phantom configuration that is realistic for myocardial perfusion imaging. The original reconstruction quality was achieved in 76 ± 8% of the original scan duration when switching from dual-energy window scatter correction to Monte Carlo-based scatter correction. The original reconstruction quality was achieved in 56 ± 13% of the original scan duration when switching from the parallel-hole to the SMARTZOOM collimator. After combining both methods in a single system, the original reconstruction quality was achieved in 34 ± 7% of the original scan duration. Monte Carlo-based scatter correction combined with the SMARTZOOM collimator can further decrease the scan duration in myocardial perfusion imaging.

中文翻译：

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基于蒙特卡洛的SMARTZOOM准直器散射校正。

心肌灌注成像是一种常用的SPECT方案，因此，如果可以缩短扫描时间，将是有益的。对于传统的伽玛相机，分别显示了两项改进以缩短扫描时间：（i）使用基于蒙特卡洛的散射校正而不是双能量窗口散射校正进行重建；（ii）使用SMARTZOOM准直仪而不是a来获取投影平行孔准直仪。这项研究调查了将两种方法组合在一个系统中可以实现的扫描时间减少。SMARTZOOM准直仪已在基于Monte Carlo的重建软件包中实现，并且该实现已通过图像质量体模实验进行了验证。减少扫描持续时间的可能性是通过幻像配置评估的，该幻像配置对于心肌灌注成像很现实。从双能量窗口散射校正切换到基于蒙特卡洛的散射校正时，原始重建质量达到了原始扫描持续时间的76±8％。从平行孔转换为SMARTZOOM准直仪时，原始重建质量达到原始扫描时间的56±13％。将这两种方法组合在一个系统中后，原始重建质量可达到原始扫描持续时间的34±7％。基于蒙特卡洛的散射校正与SMARTZOOM准直仪相结合，可以进一步减少心肌灌注成像的扫描时间。从双能量窗口散射校正切换到基于蒙特卡洛的散射校正时，原始重建质量达到原始扫描持续时间的76±8％。从平行孔转换为SMARTZOOM准直仪时，原始重建质量达到原始扫描时间的56±13％。将这两种方法结合在一个系统中后，原始重建质量可达到原始扫描持续时间的34±7％。基于蒙特卡洛的散射校正与SMARTZOOM准直仪相结合，可以进一步减少心肌灌注成像的扫描时间。从双能量窗口散射校正切换到基于蒙特卡洛的散射校正时，原始重建质量达到了原始扫描持续时间的76±8％。从平行孔转换为SMARTZOOM准直仪时，原始重建质量达到原始扫描时间的56±13％。将这两种方法结合在一个系统中后，原始重建质量可达到原始扫描持续时间的34±7％。基于蒙特卡洛的散射校正与SMARTZOOM准直仪相结合，可以进一步减少心肌灌注成像的扫描时间。从平行孔转换为SMARTZOOM准直仪时，原始重建质量达到原始扫描时间的56±13％。将这两种方法结合在一个系统中后，原始重建质量可达到原始扫描持续时间的34±7％。基于蒙特卡洛的散射校正与SMARTZOOM准直仪相结合，可以进一步减少心肌灌注成像的扫描时间。从平行孔转换为SMARTZOOM准直仪时，原始重建质量达到原始扫描时间的56±13％。将这两种方法结合在一个系统中后，原始重建质量可达到原始扫描持续时间的34±7％。基于蒙特卡洛的散射校正与SMARTZOOM准直仪相结合，可以进一步减少心肌灌注成像的扫描时间。