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A study in first-episode psychosis patients: does angiotensin I-converting enzyme (ACE) activity associated with genotype predict symptoms severity reductions after treatment with the atypical antipsychotic risperidone?
International Journal of Neuropsychopharmacology ( IF 4.8 ) Pub Date : 2020-07-22 , DOI: 10.1093/ijnp/pyaa050 João V Nani 1, 2, 3 , Caroline Dal Mas 1 , Camila M Yonamine 1 , Vanessa K Ota 4 , Cristiano Noto 2, 5 , Sintia I Belangero 4 , Jair J Mari 2 , Rodrigo Bressan 2 , Quirino Cordeiro 5 , Ary Gadelha 2 , Mirian A F Hayashi 1, 3
International Journal of Neuropsychopharmacology ( IF 4.8 ) Pub Date : 2020-07-22 , DOI: 10.1093/ijnp/pyaa050 João V Nani 1, 2, 3 , Caroline Dal Mas 1 , Camila M Yonamine 1 , Vanessa K Ota 4 , Cristiano Noto 2, 5 , Sintia I Belangero 4 , Jair J Mari 2 , Rodrigo Bressan 2 , Quirino Cordeiro 5 , Ary Gadelha 2 , Mirian A F Hayashi 1, 3
Affiliation
Our previous studies showed increased angiotensin I-converting enzyme (ACE) activity in chronic schizophrenia (SCZ) patients compared to healthy control (HC) volunteers, and the relevance of combining ACE genotype and activity for predicting SCZ was suggested.
中文翻译：
一项针对首发精神病患者的研究：与基因型相关的血管紧张素 I 转换酶 (ACE) 活性是否可以预测非典型抗精神病药物利培酮治疗后症状严重程度的减轻？
我们之前的研究表明，与健康对照（HC）志愿者相比，慢性精神分裂症（SCZ）患者的血管紧张素I转换酶（ACE）活性增加，并提出了结合ACE基因型和活性来预测SCZ的相关性。
更新日期：2020-07-22
中文翻译：
一项针对首发精神病患者的研究：与基因型相关的血管紧张素 I 转换酶 (ACE) 活性是否可以预测非典型抗精神病药物利培酮治疗后症状严重程度的减轻？
我们之前的研究表明，与健康对照（HC）志愿者相比，慢性精神分裂症（SCZ）患者的血管紧张素I转换酶（ACE）活性增加，并提出了结合ACE基因型和活性来预测SCZ的相关性。
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