The aim of this study was to evaluate the differences in the metabolic profile and body composition of monozygotic (MZ) twins concordant and discordant for the practice of physical exercise. The sample consisted of 92 MZ twins (72.5% female and 27.5% male, mean age 25.4 ± 5.69 years), registered with the Brazilian Registry of Twins, residing in Natal, Brazil. Data collection was carried out between the years 2016 and 2018. On day 1, subjects underwent a whole-body fitness evaluation, including measures of weight, height, body composition by Dual-Energy X-ray Absorptiometry and the Cardiorespiratory Exercise Test. On day 2, 10 ml blood samples were collected (overnight fasting) to determine the lipid profile and fasting glucose. The sample was separated into three groups: Active Concordant twins (Concordant A, n = 44 subjects), Inactive Concordant twins (Concordant I, n = 22 subjects) and Discordant pairs for Physical Exercise (Discordant PE, n = 26 subjects). The results demonstrated a difference between the discordant twins for exercise and also between the active versus sedentary groups, indicating a causal effect of exercise on the fat percentage, maximum oxygen consumption (VO2max) and second ventilatory threshold variables. Between groups, a difference was also observed between the groups in ventilatory threshold, very low-density lipoprotein and triglycerides. We concluded that, regardless of genetics, the practice of physical exercise was sufficient to generate alterations in body composition and VO2max in MZ twins, but not in the lipid profile or fasting glucose.

中文翻译：

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双胞胎的代谢特征和身体成分在体育锻炼方面一致和不一致

本研究的目的是评估单卵 (MZ) 双胞胎的代谢特征和身体成分在体育锻炼实践中是否一致和不一致的差异。样本包括 92 对 MZ 双胞胎（72.5% 女性和 27.5% 男性，平均年龄 25.4 ± 5.69 岁），在巴西双胞胎登记处登记，居住在巴西纳塔尔。数据收集于 2016 年至 2018 年期间进行。在第 1 天，受试者接受了全身健康评估，包括通过双能 X 射线吸收测定法和心肺运动测试测量体重、身高、身体成分。在第 2 天，收集 10 ml 血样（隔夜禁食）以确定血脂和空腹血糖。样本被分成三组：活跃的协和双胞胎（协和 A，n= 44 名受试者），不活跃的 Concordant 双胞胎（Concordant I，n= 22 名受试者）和不和谐对体育锻炼（不和谐 PE，n= 26 个科目）。结果表明，运动不协调的双胞胎之间以及活跃组与久坐组之间存在差异，表明运动对脂肪百分比、最大耗氧量（VO2最大）和第二通气阈值变量。组间，在通气阈值、极低密度脂蛋白和甘油三酯方面也观察到组间差异。我们得出的结论是，无论遗传如何，体育锻炼都足以改变身体成分和 VO2MZ 双胞胎中的最大值，但不在血脂或空腹血糖中。