Guanylate-binding proteins (GBPs) promote immune defenses against infectious agents. Two studies reveal that GBP1 directly binds to cytosolic lipopolysaccharide (LPS), bringing caspase-4 to the surface of bacteria to induce pyroptosis.

中文翻译：

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船长GBP1：炎症小体聚集，残热残光。

鸟苷酸结合蛋白（GBPs）促进针对感染因子的免疫防御。两项研究表明，GBP1直接与胞质脂多糖（LPS）结合，使caspase-4进入细菌表面以诱导发烧。