Abstract

In this study, oleanolic acid and its derivatives were studied for their invivo nematicidal activity against root-knot nematode (RKN) Meloidogyne incognita. A series of C-28-oleanolates including five new (5, 7–10) and seven known (1–4, 6, 11, 12) compounds were synthesised and their nematicidal activity was determined and compared with the standard nematicide furadan for the first time. The structures of the compounds were elucidated through ¹H NMR, ¹³C NMR and EIMS. Compounds 4, 5, 7, 8 and 10 showed ∼ 90% inhibition of RKN at 0.125% concentration after 72 h showing their potential use in nematicidal control.

摘要

在本研究中，研究了齐墩果酸及其衍生物对根结线虫 (RKN)南方根结线虫的体内杀线虫活性。合成了一系列 C-28-齐墩果酸酯，包括五种新化合物(5, 7-10)和七种已知化合物(1-4, 6, 11, 12)，测定了它们的杀线虫活性，并与标准杀线虫剂呋喃丹进行比较。第一次。化合物的结构通过¹ H NMR、¹³ C NMR 和 EIMS进行了阐明。72 小时后，化合物4、5、7、8和10在 0.125% 的浓度下显示出约 90% 的 RKN 抑制，表明它们在杀线虫控制中的潜在用途。