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Donation of discarded ocular tissue in patients undergoing SMILE laser refractive surgery: developing appropriate guidelines.
Cell and Tissue Banking ( IF 1.5 ) Pub Date : 2020-07-22 , DOI: 10.1007/s10561-020-09850-3
Mona Ghabcha 1, 2 , Gerard Sutton 1, 2, 3, 4, 5 , Con Petsoglou 1, 2, 3 , Jane Treloggen 1, 2 , Michael Lawless 3, 4 , Colin Chan 3, 4 , Chris Hodge 2, 3, 4, 6
Affiliation  

Tissue Biobanks represent an invaluable resource. Despite the majority of people supporting tissue donation, the actual rate remains low overall. Tissue discarded from surgical procedures represents a further avenue for collection for use in research. We aim to understand the information and consent requirements in a cohort of healthy, post-ophthalmic surgical subjects to optimise future tissue collection in living donors. Patients attending an ophthalmic clinic following refractive surgery for myopia (SMILE) were identified. Patient consent was implied with the completion of the provided survey. The questionnaire included gender, age range and education status. The majority of 31 subjects identified a benefit for future patients as the main motive for potential donation of discarded tissue (71%). Payment for the discarded tissue would not influence their decision in 77.4%. Explanation of the potential benefits of research was the most important information to consider before making a decision to donate. Only 12.9% of patients would have refused to include further information. Almost half of patients felt that the Biobank became the owner of tissue following donation. Current surgical patients may be more inclined to participate in research than the general public because of a sense of duty or an increased understanding of the role of research in evolving treatment. Despite minor uncertainty about the eventual use of the tissue and data, most subjects were positive to donation of discarded ocular tissue and de-identified information. Consent and education processes should be revised within an ophthalmic practice to minimise future patient anxiety.



中文翻译:

捐赠接受 SMILE 激光屈光手术的患者丢弃的眼部组织:制定适当的指南。

组织生物库是一种宝贵的资源。尽管大多数人支持组织捐赠,但总体上实际比率仍然很低。从外科手术中丢弃的组织代表了另一种收集用于研究的途径。我们旨在了解一组健康的眼科手术后受试者的信息和同意要求,以优化未来活体捐赠者的组织收集。确定了近视屈光手术 (SMILE) 后到眼科诊所就诊的患者。完成提供的调查意味着患者同意。问卷包括性别、年龄范围和教育状况。31 名受试者中的大多数将未来患者的益处确定为可能捐赠废弃组织的主要动机 (71%)。77.4% 的人为丢弃的纸巾付款不会影响他们的决定。在做出捐赠决定之前,对研究潜在益处的解释是最重要的信息。只有 12.9% 的患者会拒绝提供更多信息。几乎一半的患者认为生物库在捐赠后成为组织的所有者。由于责任感或对研究在不断发展的治疗中的作用的更多理解,当前的外科患者可能比一般公众更倾向于参与研究。尽管对组织和数据的最终使用有轻微的不确定性,但大多数受试者对捐赠丢弃的眼部组织和去识别化信息持积极态度。

更新日期:2020-07-22
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