Alterations in Microstructure and Local Fiber Orientation of White Matter Are Associated with Outcome after Mild Traumatic Brain Injury.,Journal of Neurotrauma

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Alterations in Microstructure and Local Fiber Orientation of White Matter Are Associated with Outcome after Mild Traumatic Brain Injury.
Journal of Neurotrauma ( IF 4.2 ) Pub Date : 2020-12-03 , DOI: 10.1089/neu.2020.7081
Mehrbod Mohammadian _{1,

2} , Timo Roine _{3,

4} , Jussi Hirvonen ₅ , Timo Kurki _{1,

2,

5} , Jussi P Posti _{1,

2,

6} , Ari J Katila _{7,

8} , Riikka S K Takala _{7,

8} , Jussi Tallus _{1,

2} , Henna-Riikka Maanpää _{2,

6} , Janek Frantzén _{1,

6} , Peter J Hutchinson ₉ , Virginia F Newcombe ₁₀ , David K Menon ₁₀ , Olli Tenovuo _{1,

2}

Affiliation

Department of Clinical Neurosciences, Intensive Care, Emergency Care and Pain Medicine, University of Turku, Turku, Finland.
Turku Brain Injury Center, Intensive Care Medicine and Pain Management, Turku University Hospital, Turku, Finland.
Turku Brain and Mind Center, Intensive Care, Emergency Care and Pain Medicine, University of Turku, Turku, Finland.
Department of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland.
Department of Radiology, Intensive Care, Emergency Care and Pain Medicine, University of Turku, Turku, Finland.
Department of Neurosurgery, Division of Clinical Neurosciences, Intensive Care Medicine and Pain Management, Turku University Hospital, Turku, Finland.
Perioperative Services, Intensive Care Medicine and Pain Management, Turku University Hospital, Turku, Finland.
Anesthesiology, Intensive Care, Emergency Care and Pain Medicine, University of Turku, Turku, Finland.
Department of Clinical Neurosciences, Neurosurgery Unit, Addenbrooke's Hospital, Cambridge, United Kingdom.
Division of Anesthesia, Addenbrooke's Hospital, Cambridge, United Kingdom.

Mild traumatic brain injury (mTBI) can have long-lasting consequences. We investigated white matter (WM) alterations at 6–12 months following mTBI using diffusion tensor imaging (DTI) and assessed if the alterations associate with outcome.

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