It is conventionally understood that occlusive effects are the retention of excessive water in the stratum corneum (SC), the increase of SC thickness (swelling) and a decrease of the transepidermal water loss. However, the influence of occlusion on water binding properties in the SC is unknown.

中文翻译：

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角质层闭塞诱导水向较低结合状态转变：通过共焦拉曼显微光谱进行的分子水平体内研究。

通常认为，闭塞效应是角质层(SC)中过多的水分滞留、SC厚度的增加(肿胀)和经皮水分流失的减少。然而，闭塞对 SC 中的水结合特性的影响尚不清楚。