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A new house dust mite‐driven and mast cell‐activated model of asthma in the guinea pig
Clinical & Experimental Allergy ( IF 6.1 ) Pub Date : 2020-08-05 , DOI: 10.1111/cea.13713
Patricia Ramos-Ramírez 1 , Malin Noreby 1 , Jielu Liu 1 , Jie Ji 2 , Suado M Abdillahi 2 , Henric Olsson 3 , Sven-Erik Dahlén 1 , Gunnar Nilsson 4 , Mikael Adner 1
Affiliation  

Animal models are extensively used to study underlying mechanisms in asthma. Guinea pigs share anatomical, pharmacological and physiological features with human airways and may enable the development of a pre‐clinical in vivo model that closely resembles asthma.

中文翻译:

一种新的屋尘螨驱动和肥大细胞激活的豚鼠哮喘模型

动物模型被广泛用于研究哮喘的潜在机制。豚鼠与人类呼吸道具有解剖学、药理学和生理学特征,可能有助于开发与哮喘非常相似的临床前体内模型。
更新日期:2020-08-05
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